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OCR: ated with The clinical symptoms that may be asso medullary carcinoma of the thyroid are summarised in Figs. 16.20. The diarrhoea is severe and watery due ssive combination of intestinal hurry and exce tumour secretion. It is relieved by removal of th the and recurs with metastases. The cause of itonin, a secretion has not been identified but calo landins, bradykinin-producing kallikrein, prosta I been and vasoactive intestinal peptide have a ave been implicated. The peptide hormones that ood are identified in tumour tissue and in the b calcitonin also listed in Fig. 16.20. The basal level o ve infusionis high and rises greatly after a provocati of ionised calcium or following the oral administration of alcohol or pentagastri See later: . Metastasis in Thyroid Malignancy